Glyceryl Diesters

Author:

Raj Preethi S.1,Bergfeld Wilma F.2,Belsito Donald V.2,Cohen David E.2,Klaassen Curtis D.2,Liebler Daniel C.3,Rettie Allan E.2,Ross David2,Slaga Thomas J.2,Snyder Paul W.2,Tilton Susan2,Fiume Monice4,Heldreth Bart5

Affiliation:

1. Cosmetic Ingredient Review Senior Scientific Analyst/Writer

2. Expert Panel for Cosmetic Ingredient Safety Member

3. Expert Panel for Cosmetic Ingredient Safety Former Member

4. Cosmetic Ingredient Review Senior Director

5. Cosmetic Ingredient Review Executive Director

Abstract

The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that these 17 glyceryl diesters are safe as cosmetic ingredients in the practices of use and concentration as described in this report.

Funder

Personal Care Products Council

Publisher

SAGE Publications

Subject

Toxicology

Reference27 articles.

1. Bergfeld WF, Belsito DV, Klaasseen CD, et al. Final report of the cosemtic ingredient review expert panel. Safety assessment of glyceryl dilaurate, glyceryl diarachidate, glyceryl dibehenate, glyceryl dierucate, glyceryl dihydroxystearate, glyceryl diisopalmitate, glyceryl diisostearate, glyceryl dilinoleate, glyceryl dimyristate, glyceryl dioleate, glyceryl dipalmitate, glyceryl dipalmitoleate, glyceryl distearate, glyceryl palmitate lactate, glyceryl stearate citrate, glyceryl stearate lactate, and glyceryl stearate succinate. 2002, Available from CIR. https://www.cir-safety.org/ingredients

2. U.S. Food and Drug Administration Center for Food Safety & Applied Nutrition (CFSAN). Voluntary cosmetic registration Program - Frequency of use of cosmetic ingredients (VCRP). Obtained under the freedom of information act from CFSAN; requested as “Frequency of use data” January 4, 2022; Received January 11, 2022. 2022.

3. Personal Care Products Council. Concentration of use by FDA product category: Glyceryl diesters. Unpublished data submitted by the Personal Care Products Council on July 7, 2022. 2022.

4. Photoswitchable diacylglycerols enable optical control of protein kinase C

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