Dioscorea Villosa (Wild Yam) Root Extract

Author:

Raj Preethi S.1,Bergfeld Wilma F.2,Belsito Donald V.2,Cohen David E.2,Klaassen Curtis D.2,Rettie Allan E2,Ross David2,Slaga Thomas J.2,Snyder Paul W.2,Tilton Susan2,Fiume Monice3,Heldreth Bart4

Affiliation:

1. Cosmetic Ingredient Review Senior Scientific Analyst/Writer

2. Expert Panel for Cosmetic Ingredient Safety Member

3. Cosmetic Ingredient Review Senior Director

4. Cosmetic Ingredient Review Executive Director

Abstract

The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 2004, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Dioscorea Villosa (Wild Yam) Root Extract is safe as a cosmetic ingredient in the practices of use and concentration as described in this report.

Funder

Personal Care Products Council

Publisher

SAGE Publications

Subject

Toxicology

Reference9 articles.

1. U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition (CFSAN). Voluntary cosmetic registration Program - frequency of use of cosmetic ingredients (VCRP). (Obtained under the freedom of information act from CFSAN; requested as “frequency of use data”. 2022. (January 4, 2022; received January 11, 2022).

2. Personal Care Products Council. Concentration of use by FDA product category: Dioscorea Villosa (Wild Yam) root extract. 2022. (Unpublished data submitted by the Personal Care Products Council on October 31, 2022).

3. Bioassay-guided evaluation of Dioscorea villosa – an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach

4. Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways

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