1. Toxicology and Biomedicine Center (TOXIMED), Medical Science University of Santiago de Cuba, Santiago de Cuba, Cuba
2. São Paulo Estate University (UNESP), Pharmaceutical Sciences Faculty, Araraquara, Brazil
3. Department of Biology, Faculty of Natural Sciences, University of Oriente, Santiago de Cuba, Cuba
4. Faculty of Chemical Enginery, University of Oriente, Santiago de Cuba, Cuba
5. Department of Immunology, University of Medical Science, Havana, Cuba