Affiliation:
1. Cosmetic Ingredient Review Scientific Analyst/Writer
2. Cosmetic Ingredient Review Expert Panel Member
3. Director, Cosmetic Ingredient Review
Abstract
Caprylyl glycol and related 1,2-glycols are used mostly as skin and hair conditioning agents and viscosity agents in cosmetic products, and caprylyl glycol and pentylene glycol also function as cosmetic preservatives. The Cosmetic Ingredient Review (CIR) Expert Panel noted that, while these ingredients are dermally absorbed, modeling data predicted decreased skin penetration of longer chain 1,2-glycols. Because the negative oral toxicity data on shorter chain 1,2-glycols and genotoxicity data support the safety of the 1,2-glycols reviewed in this safety assessment, the Panel concluded that these ingredients are safe in the present practices of use and concentration described in this safety assessment.
Reference71 articles.
1. Final Report on the Safety Assessment of Propylene Glycol and Polypropylene Glycols
2. Fiume MZ, Bergfeld WF, Belsito DV, Amended Final Safety Assessment of Propylene Glycol, Tripropylene Glycol, and Polypropylene Glycols. Washington, DC: Cosmetic Ingredient Review; 2010:1–31.
3. Ramakers B. United States Patent No. 7,459,589 B2. Process for the preparation of an alkylene glycol. 2008.
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