Incidental Finding on Lower-Extremity Venous Duplex Ultrasound: Vascularized Mass

Abstract

Nodular fasciitis is an uncommon pathologic finding that mimics the clinical presentation of sarcoma. The similar characteristics of a rapidly invasive growth pattern and abundant cellularity frequently causes nodular fasciitis to be misdiagnosed as sarcoma. Nodular fasciitis has been known to pathologists since the 1940s, yet few discussions have been presented in the literature. Large, high-grade sarcomas have a 79% recurrence rate, with 60% of these patients dying from the disease. Recurrences typically occur within 2 years of the treatment of the original tumor. Because of the aggressive nature of this cancer, early diagnosis and treatment is critical for a favorable prognosis. The ease with which nodular fasciitis can be confused both clinically and histologically with a malignant tumor makes it essential to recognize this distinct entity as benign to avoid unnecessary interventions. More awareness is needed of this entity in assuring more accurate diagnosis and appropriate interventions.