Lanthanide chelates as new fluorochrome labels for cytochemistry.

Author:

Soini E J,Pelliniemi L J,Hemmilä I A,Mukkala V M,Kankare J J,Fröjdman K

Abstract

Anti-rabbit IgG labeled with a new fluorescent europium chelate was used to localize rabbit IgG to human smooth muscle myosin in a histological section. The antibody labeled with the europium chelate could be viewed with a conventional fluorescence microscope with a steady-state light source. This result encourages the development of a time-resolved fluorescence microscope, because a significant improvement in the signal-to-noise ratio can be anticipated.

Publisher

SAGE Publications

Subject

Histology,Anatomy

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