The Blood Coagulation and Fibrinolytic Enzyme Systems in Healthy Adult Africans and Europeans — A Comparative Study

Author:

Barr R. D.1,Ouna N.1,Kendall A. G.1

Affiliation:

1. Department of Medicine, University of Nairobi, Nairobi, Kenya

Abstract

In a comparative study of blood coagulation and fibrinolysis in healthy adult East Africans and Europeans, the Europeans were found to have some evidence of a relatively hypercoagulable state, and the European male had significantly reduced fibrinolytic activity and potential when compared to the African male. A parallel is drawn with the known prevalence of atheroma and thrombo-embolic disease in these populations and the suggestion made that the greater fibrinolytic activity of the African, perhaps resulting from a radically different diet, may account in large part for his relative freedom from atheromatous vascular disease.

Publisher

SAGE Publications

Subject

General Medicine

Reference36 articles.

1. Alkjaersig N. (1960). In N.I.H. Conference on Thrombolytic Agents p. 316. Edited by Roberts H. R., Geraty J. D., London: Chapel Hill.

2. Analytical Review: Fibrinolysis in the Organism

3. Idiopathic gangrene in African adults.

4. Biggs R., Macfarlane R. G. (1966). In Treatment of Haemophilia and Other Coagulation Disorders p. 344. Oxford: Blackwell.

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