Liver Disease in Rheumatoid Arthritis

Author:

Mills P. R.1,MacSween R. N. M.1,Dick W. C.1,More I. A.1,Watkinson G.1

Affiliation:

1. Gartnavel General Hospital, Western Infirmary and Centre for Rheumatic Diseases, Glasgow

Abstract

Patients with active rheumatoid arthritis frequently have hepatosplenomegaly and biochemical features of hepatic disease. A prospective study with liver biopsy has been carried out in a series of 31 rheumatoid arthritis patients with clinical and/or biochemical evidence of hepatic dysfunction. Four of the 31 (13%) were found to have definable chronic liver disease, normal hepatic histology or non-specific reactive changes being found in the remainder. In the large majority of patients the hepatic abnormality in rheumatoid arthritis remains functional and unexplained.

Publisher

SAGE Publications

Subject

General Medicine

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