The polypill in the primary prevention of heart attacks and strokes: Overcoming barriers to implementation

Author:

Wald Nicholas J12ORCID,Hingorani Aroon D13,Vale Stephen H4ORCID,Bestwick Jonathan P5ORCID,Morris Joan2

Affiliation:

1. Institute of Health Informatics, University College London, London, UK

2. Population Health Research Institute, St Georges University of London, London, UK

3. 3Institute of Cardiovascular Science, University College London, London, UK

4. Logical Medical Systems, London, UK

5. Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, UK

Abstract

This commentary, linked to our paper in the same issue of the Journal of Medical Screening, discusses the reluctance to consider and adopt the polypill in the primary prevention of heart attacks and strokes, access to the polypill as a public health service, the formulation of the polypill in current use, its prescription as an unlicensed medicine, and what can be done to facilitate the adoption of the polypill approach as a routine public health service.

Publisher

SAGE Publications

Reference23 articles.

1. Huffman M., Agarwal A, Zhu JJ, et al. An application to include fixed dose combinations in the WHO model list of essential medicines for primary and secondary prevention of atherosclerotic cardiovascular diseases in adults. https://cdn.who.int/media/docs/default-source/essential-medicines/2023-eml-expert-committee/applications-for-addition-of-new-medicines/a16_cvd-fdc.pdf?sfvrsn=a9d4588_2 (accessed 23 February 2024).

2. Comparing screening based on the NHS Health Check and Polypill Prevention Programmes in the primary prevention of heart attacks and strokes

3. The Polypill at 20 — What Have We Learned?

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