Affiliation:
1. School of Plant Protection, Anhui Agricultural University, Hefei, China
2. Tobacco Research Institute of Chinese Academy of Agricultural Sciences, Qingdao, China
3. Fujian Agriculture and Forestry University, Fuzhou, China
Abstract
A phytochemical investigation of an aqueous ethyl alcohol (EtOH) extract of the flowers of Nicotiana tabacum L . led to the identification of one new eudesmane-type sesquiterpenoid (1) and 14 known compounds, including 7 flavones (2-8), 6 phenolic acids (9-14), and 1 coumarin (15). The chemical structure of 1 was established on the basis of high-resolution electrospray ionization (HRESIMS) and 1D and 2D NMR analyses, while the other structures were elucidated by 1D NMR and LC–MS data. The antiphytopathogenic activities of all the isolated compounds were tested to determine their antifungal activity against Valsa mali var. mali, Alternaria porri, and Botrytis cinerea at a concentration of 10 µg/mL. Compound 4 exhibited more potent antifungal effects against Valsa mali var. mali with a % growth inhibition of 47.9 ± 1.2%, while the others only showed insignificant activities.
Funder
the Science Foundation for Young Scholars of Tobacco Research Institute of Chinese Academy of Agricultural Sciences
the Foundation of Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences
the Agricultural Science and Technology Innovation Program
the Foundation of Key Laboratory of Biopesticide and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine
Reference20 articles.
1. China Flora Editorial Board (Chinese Academy of Sciences). Flora of China, Vol. 67. Science Press; 1978:152-153.
Cited by
3 articles.
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