X-ray Crystallographic Study of Ranaconitine-Reference-Cited by-同舟云学术

X-ray Crystallographic Study of Ranaconitine

Published:2011-11 Issue:11 Volume:6 Page:1934578X1100601
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Li Yang¹²,Zhou Jun-Hui¹³,Han Gui-Jun³,Wang Min-Juan⁴,Sun Wen-Ji²,Zhao Ye²

Affiliation:

1. These authors contributed equally to this work.

2. Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an, Shaanxi, 710069, P.R. China

3. Xi'an Botanical Garden, Institute of Botany of Shaanxi Province, Xi'an, Shaanxi, 710061, P.R. China

4. Center for Disease Control and Prevention of Shaanxi Province, Xi'an, Shaanxi, 710054, P.R.China

Abstract

The crystal structure of natural diterpenoid alkaloid ranaconitine isolated from Aconitum sinomontanum Nakai has been determined by single crystal X-ray diffraction analysis. The crystal presents a monoclinic system, space group C2 with Z = 4, unit cell dimensions a = 30.972(19) Å, b = 7.688(5) Å, and c = 19.632(12) Å. Moreover, the intermolecular O–H···O hydrogen bonds and weak π-π interactions play a critical role in expanding the dimensionality.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1100601107

Reference6 articles.

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3. The structure of ranaconitine, a new diterpenoid alkaloid of

4. General definition of ring puckering coordinates