A Novel Anticancer Diterpenoid from Jatropha Gossypifolia-Reference-Cited by-同舟云学术

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A Novel Anticancer Diterpenoid from Jatropha Gossypifolia

Published:2012-02 Issue:2 Volume:7 Page:1934578X1200700
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Falodun Abiodun¹,Kragl Udo²,Touem Serge-Mitherand Tengho²,Villinger Alexander²,Fahrenwaldt Thomas²,Langer Peter²

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin City, Nigeria, Edo State, 30001

2. Institut fuer Chemie, Universitat Rostock, Albert-Einstein-Straße 3a, 18059, Rostock, Germany

Abstract

Jatropha gossypifolia root bark is used in ethnomedicine for bacterial infections and cancer of the lungs. Phytochemical investigation resulted in the isolation and characterization of a potent anticancer and novel lathyrane diterpenoid compound, abiodone, with an unusual methylene group. The structure of this novel compound was established by 1D, and 2D NMR spectroscopic experiments and confirmed by X-ray analysis.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1200700204

Reference12 articles.

1. SastriBN. (1959) The Wealth of India, Raw Materials, Vol. V, p.295. CSIR, New Delhi.

2. ChopraRN, NayarSL, ChopraIC. (1956) Glossary of Indian Medicinal Plants, CSIR, New Delhi. 145.

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