Composition of Satureja kitaibelii Essential Oil and its Antimicrobial Activity

Author:

Kundaković Tatjana1,Milenković Marina2,Zlatković Saša3,Kovačević Nada1,Goran Nikolić4

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia

2. Department of Microbiology and Immunology, University of Belgrade, Faculty of Pharmacy, Vojvode Stepe 450, 11221 Belgrade, Serbia

3. Actavis Trading Ltd, Djordja Stanojevica 12, Novi Beograd 11070, Serbia

4. Department of Organic Chemical Technology, University of Niš, Faculty of Technology, Bulevar oslobođenja 124, 16000 Leskovac, Serbia

Abstract

The composition of the essential oil obtained by hydrodistillation from the aerial parts of Satureja kitaibelii from Rtanj mountain (Serbia), collected during three years, was studied. Thirty-nine components were identified in each sample of S. kitaibelii essential oil, representing about 87% of the oils. p-Cymene was the most dominant compound in all three oils (27.9%, 14.7% and 24.4%, respectively). The simple formulation of a lozenge with 0.2% of S. kitaibelii essential oil was prepared and the antimicrobial activity of the essential oil and the lozenge with essential oil was tested using a broth microdilution assay. Both essential oil and lozenge possessed strong antimicrobial activity with MIC values of 0.10-25 μg/mL, and 0.97-15.6 mg/mL, respectively.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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