Chemical Composition and Antibacterial Activity of the Essential Oil of Espeletia nana-Reference-Cited by-同舟云学术

Chemical Composition and Antibacterial Activity of the Essential Oil of Espeletia nana

Published:2012-05 Issue:5 Volume:7 Page:1934578X1200700
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Peña Alexis¹,Rojas Luis²,Aparicio Rosa²,Alarcón Libia³,Baptista José Gregorio³,Velasco Judith⁴,Carmona Juan⁵,Usubillaga Alfredo²

Affiliation:

1. Postgrado Interdisciplinario en Química Aplicada, Facultad de Ciencias, Universidad de Los Andes, Mérida, Venezuela

2. Instituto de Investigación, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela

3. Departamento de Biología y Química. Núcleo Universitario Rafael Rangel Universidad de Los Andes, Trujillo, Venezuela

4. Departamento de Microbiología y Parasitología. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela

5. Jardín Botánico de la Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela

Abstract

The essential oil of the leaves of Espeletia nana Cuatrec, obtained by hydrodistillation, was analyzed by GC-MS, which allowed the identification of 24 components, which made up 99.9% of the oil. The most abundant compounds were α-pinene (38.1%), β-pinene (17.2%), myrcene (15.0%), spathulenol (4.2%), bicyclogermacrene (4.0%), α-zingiberene (4.0%), and γhimachalene (3.7%). Antibacterial activity was tested against Gram-positive and Gram-negative bacteria using the agar disk diffusion method. Activity was observed only against Gram-positive bacteria. MIC values were determined for Staphylococcus aureus ATCC 25923(200 μg/mL) and Enterococcus faecalis ATCC 29212 (600 μg/mL).

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1200700530

Reference17 articles.

1. Composition of the essential oil of four species ofRuilopezia from the Venezuelan Andes

2. Volatile constituents from the leaves of fourLibanothamus species from the Venezuelan Andes

3. Chemical Composition and Antimicrobial Activity of the Essential Oils ofPistacia lentiscusvar.chia

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