Coumestan Glycosides from the Stem Bark of Cylicodiscus Gabunensis-Reference-Cited by-同舟云学术

Coumestan Glycosides from the Stem Bark of Cylicodiscus Gabunensis

Published:2009-07 Issue:7 Volume:4 Page:1934578X0900400
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Nchancho Kazie¹,Kouam Jacques¹,Tane Pierre²,Kuete Victor²,Watchueng Jean³,Fomum Zacharias T.¹

Affiliation:

1. Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, PO Box 812, Cameroon

2. Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67, Cameroon

3. Institut de recherche en Biotechnologie de Montréal, 6100 Avenue Royalmount, H4P 2R2, Canada

Abstract

Two new coumestan glycosides, coumestoside C (1) and coumestoside D (2), were isolated from the stem bark of Cylicodiscus gabunensis Harms. Their structures were established by spectroscopic means and chemical transformations as 9- O-α-L-rhamnopyranosyl-3-hydroxy-4-(5′-hydroxy-3′-methylbut-2′ E-enyl) coumestan (1) and 9- O-β-D-galactopyranosyl-3- O- prenyl-4-hydroxycoumestan. Coumestoside C exhibited antimicrobial activity against Proteus vulgaris.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0900400711

Reference9 articles.

1. Coumestoside A, Coumestoside B and Erythrodiside A, Three Glycosides from Cylicodiscus gabunensis (Mimmosaceae)

2. Antioxidant 2-Phenylbenzofurans and a Coumestan from Lespedeza virgata

3. Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens?

4. Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

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