Antimicrobial Activity of two Semisynthetic Triterpene Derivatives from Euphorbia Officinarum Latex Against Fungal and Bacterial Phytopathogens-Reference-Cited by-同舟云学术

Antimicrobial Activity of two Semisynthetic Triterpene Derivatives from Euphorbia Officinarum Latex Against Fungal and Bacterial Phytopathogens

Published:2017-03 Issue:3 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Smaili Amal¹,Mazoir Noureddine²³,Rifai Lalla Aicha¹,Koussa Tayeb¹,Makroum Kacem¹,Benharref Ahmed³,Faize Lydia⁴,Alburquerque Nuria⁴,Burgos Lorenzo⁴,Belfaiza Malika¹,Faize Mohamed¹

Affiliation:

1. Laboratory of Plant Biotechnology and Ecosystem Valorisation, Faculty of Sciences, University Chouaib Doukkali, El Jadida, Morocco

2. Department of Chemistry, Faculty of Sciences El Jadida, Chouaib Doukkali University, P.O. Box 20, 24000 El Jadida, Morocco

3. Laboratory of Biomolecular Chemistry, Natural Substances and Reactivity, URAC 16, Faculty of Sciences Semlalia, Cadi Ayyad University, P.O. Box 2390, Marrakech, Morocco

4. Group of Fruit Tree Biotechnology, Department of Plant Breeding, CEBAS-CSIC, PO Box 164, 30100 Murcia, Spain

Abstract

This study evaluated the in vitro antimicrobial effect of 3β-acetoxy-norlup-20-one (1) and 3-chloro-4α,14α-dimethyl-5α-cholest-8-ene (2), triterpene derivatives from Euphorbia officinarum latex against fungal and bacterial phytopathogens. Results showed that although mycelial growth of several strains of Verticillium dahlia, and Fusarium oxysporum fsp. melonis and Penicillium expansum was affected only moderately, the two compounds were able to reduce highly conidia formation and germination, suggesting that they act as fungistatic compounds. Their antibacterial activity was tested against Pseudomonas syringae pv. syringae (Pss), P. syringae pv. tabacci (Pst), Erwinia amylovora (Ea) and Agrobacterium tumefaciens (At) using disc diffusion method. Results showed that compound 2 was more effective in inhibiting the growth of Pss, Pst and Ea than compound 1.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200305

Reference40 articles.

1. Pesticide Exposure, Safety Issues, and Risk Assessment Indicators

2. Fungicide resistance: facing the challenge – a review

3. Discovery and resupply of pharmacologically active plant-derived natural products: A review

4. The genetics and molecular genetics of terpene and sterol origami

5. Triterpenoids

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