Constituents of the Leaves of Pandanus Utilis-Reference-Cited by-同舟云学术

Constituents of the Leaves of Pandanus Utilis

Published:2016-02 Issue:2 Volume:11 Page:1934578X1601100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Lo I-Wen¹,Cheng Yuan-Bin¹,Haung Chen-Chang¹,Hwang Tsong-Long²,Wu Chin-Chung¹,Liou Jing-Ru¹,Hou Ming-Feng³,Yuan Shyng-Shiou⁴,Chang Fang-Rong¹³⁵⁶,Wu Yang-Chang⁷⁸⁹¹⁰

Affiliation:

1. Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

2. Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan

3. Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan

4. Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

5. Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

6. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan

7. School of Pharmacy, College of Pharmacy, China Medical University, Taichung 40402, Taiwan

8. Research Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan

9. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 40402, Taiwan

10. Center of Molecular Medicine, China Medical University Hospital, Taichung 40402, Taiwan

Abstract

Nineteen compounds, including seven triterpenoids (1–7), five steroids (8–12), four cyclohexenone derivatives (13–16), two benzenoid glycosides (17 and 18) and one lignan (19), were isolated and separated from the leaves of Pandanus utilis through bioactivity-guided fractionation. Among them, one new lanosterol-type triterpenoid was found and named as (24 R)-24-methyl-5α-4-demethyllanosta-9(11),25-dien-3β-ol (1). The structures of the isolates were determined by mass and spectroscopic analyses, and the compounds were subjected to anti-inflammatory, anti-oxidative and cytotoxic assays.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601100209

Reference26 articles.

1. The genus Pandanus in the Mascarene Islands.

2. Hypoglycemic Effect of Water Extract of the Root of Pandanus odorus RIDL.

3. 4-Hydroxybenzoic acid: a hypoglycemic constituent of aqueous extract of Pandanus odorus root

4. Possible Mechanism of Hypoglycemic Effect of 4-Hydroxybenzoic Acid, a Constituent of Pandanus odorus Root

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