Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants

Author:

Nagashima Fumihiro12,Tabuchi Yuki1,Ito Takuya13,Harinantenaina Liva14,Asakawa Yoshinori1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, Japan 770-8514

2. Daiichi University of Pharmacy, 22-1 Tamagawa-cho Minami-ku, Fukuoka 815-8511, Japan

3. Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan

4. College of Pharmacy, The Ohio State University, 217 Lloyd M, Parks Hall, 500 West 12th Avenue, Columbus, OH 43210, USA

Abstract

Humulanes, drimanes, ent-kaurane, lupane, cycloartane, flavanone, flavones and quinol derivatives were isolated from Malagasy Cussonia vantsilana, Helichrysum gymnocephalum, Phyllarthron madagascariense, Gomphocarpus fructicosus, Cinnamosma sp. and C. fragrans, and their structures elucidated by using extensive NMR analysis. A mixture of a few flavones and/or lupane triterpene showed antimicrobial activity against Mycobacterium smegmatis and Pseudomonas aeruginosa.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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