Diversity in Chemical Constituents of Ligularia Longihastata Collected in China

Author:

Okamoto Yasuko1,Taniguchi Mizuho1,Terada Kaori2,Nakashima Katsuyuki1,Gong Xun3,Hanai Ryo4,Tori Motoo1,Kuroda Chiaki2

Affiliation:

1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, 770-8514 Japan

2. Department of Chemistry and Research Center for Smart Molecules, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

3. Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, China

4. Department of Life Science and Research Center for Life Science, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

Abstract

Root constituents of Ligularia longihastata were examined for the first time. Fourteen eremophilane sesquiterpenes, including two new eremophilanes identified as 3α-isobutyroyloxy-7β H-eremophila-9,11-dien-8-one and 3β-angeloyloxy-1β,10β-epoxyfuranoeremophilan-9-one, and three eudesmanes were isolated. From samples collected in Baiyu County, Sichuan Province, furanoeremophilane derivatives were isolated, while various eremophilan-8-ones were isolated from samples collected in Kangding County, Sichuan. The results suggest chemical diversity in the species.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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