The Iridoid Myodesert-1-ene and Elemol/Eudesmol are found in Distinct Chemotypes of the Australian Aboriginal Medicinal Plant Eremophila dalyana(Scrophulariaceae)-Reference-Cited by-同舟云学术

The Iridoid Myodesert-1-ene and Elemol/Eudesmol are found in Distinct Chemotypes of the Australian Aboriginal Medicinal Plant Eremophila dalyana(Scrophulariaceae)

Published:2016-09 Issue:9 Volume:11 Page:1934578X1601100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Sadgrove Nicholas J.¹,Collins Timothy L.²,Legendre Sarah V.A.-M.¹,Klepp Julian¹,Jones Graham L.¹,Greatrex Ben W.¹

Affiliation:

1. School of Science and Technology, University of New England, Armidale, NSW, 2351, Australia

2. School of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia

Abstract

The strongly aromatic Australian desert species Eremophila dalyana is an Aboriginal medicinal plant that continues to be used today in Central Australia in the treatment of respiratory complaints and Sarcoptes scabiei infestation. Using hydrodistillation of aerial parts of the plant, the new natural product myodesert-1-ene was isolated in two disjunct populations at up to 98% of the volatiles present in the hydrodistilled oils. Weak antimicrobial activities were observed for whole oils and myodesert-1-ene. Activities in the hydrodistilled oil were attributed to the antimicrobial sesquiterpenes elemol and eudesmol which showed good activity when isolated and were relatively abundant in the chemotype used medicinally. The biogenesis of myodesert-1-ene from iridodial is proposed.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601100902

Reference19 articles.

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4. The ethnopharmacology and phytochemistry of Eremophila species (Myoporaceae)

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