Synthesis of a 4H-anthra[1,2-b]pyran Derivative and its Antimicrobial activity-Reference-Cited by-同舟云学术

Synthesis of a 4H-anthra[1,2-b]pyran Derivative and its Antimicrobial activity

Published:2011-06 Issue:6 Volume:6 Page:1934578X1100600
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Hussain Hidayat¹,Aziz Shahid¹,Schulz Barbara²,Krohn Karsten¹

Affiliation:

1. Department of Chemistry, Universität Paderborn, Warburger Straβe 100, 33098 Paderborn, Germany

2. Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstraβe 7, 31806 Braunschweig, Germany

Abstract

The five-step synthesis of the new 4 H-anthra[1,2- b]pyran derivative 1 is reported. The key steps in this approach included a Marschalk alkylation of 1,4-dihydroxyanthraquinone followed by a Baker–Venkataraman reaction and then an acid-catalyzed cyclization of ring A to form the 4H-anthra[1,2-b]pyran system. Two compounds, the 4H-anthra[1,2-b]pyran 1 and the anthraquinone derivative 6 were evaluated for antimicrobial activity and showed moderate antialgal, antifungal, and antibacterial activities.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1100600621

Reference8 articles.

1. The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin

2. Novel Human Topoisomerase I Inhibitors, Topopyrones A, B, C and D. I. Producing Strain, Fermentation, Isolation, Physico-chemical Properties and Biological Activity.

3. A Novel Neuronal Cell Protecting Substance, Espicufolin, Produced by Streptomyces sp. cu39.

4. Synthetische Anthracyclinone, VI Synthese strukturanaloger Anthracyclinone

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cholesterol-Based B-Ring 2H-Pyran: Synthesis and Reaction Mechanism by Using Density Functional Theoretical Study;Letters in Organic Chemistry;2024-11

2. Selective Hydrogenation of Quinizarins to Leuco-quinizarins and Their Direct Derivatization Using Flow-Batch-Separator Unified Reactors under Continuous-Flow Conditions;ACS Catalysis;2024-06-24

3. Succinimidium Perchlorate as a Novel and Efficient Brönsted Acidic Ionic Liquid Promoter for the Synthesis of 5-arylidene Barbituric Acid and pyrano[2,3-d] Pyrimidinone Derivatives;Current Organocatalysis;2023-12

4. Synthesis, molecular docking analysis and in-vitro evaluation of 1,4-dihydroxyanthraquinone derivatives as anti-trypanosomal agents;Letters in Organic Chemistry;2022-11-14

5. Recent Progress in the Multicomponent Synthesis of Pyran Derivatives by Sustainable Catalysts under Green Conditions;Molecules;2022-09-26