Solid State Structure and Absolute Configuration of Filifolinol Acetate-Reference-Cited by-同舟云学术

Solid State Structure and Absolute Configuration of Filifolinol Acetate

Published:2011-06 Issue:6 Volume:6 Page:1934578X1100600
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Muñoz Marcelo A.¹,Urzúa Alejandro²,Echeverría Javier²,Modak Brenda²,Joseph-Nathan Pedro³

Affiliation:

1. Instituto de Ciéncias Químicas, Universidad Austral de Chile, Casilla 567, Valdivia, Chile

2. Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile

3. Departamento de Química, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Apartado 14-740, México, D. F., 07000 México

Abstract

Careful reevaluation of the 1H and 13C NMR spectroscopic data of filifolinol acetate (4) led to the reassignment of the C-10 and C-11 signals, as well as the gem-dimethyl signals. Single crystal X-ray analysis provided an independent structural confirmation of 4, and comparison of the experimental vibrational circular dichroism spectrum with calculations performed using density functional theory provided the absolute configuration of this 3H-spiro-1-benzofuran-2,1′-cyclohexane and related molecules.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1100600604

Reference11 articles.

1. Filifolinol, a rearranged geranyl aromatic derivative from the resinous exudate of Heliotropium filifolium

2. Antibacterial Properties of 3 H-Spiro[1-benzofuran-2,1’-cyclohexane] Derivatives from Heliotropium filifolium

3. PROPIEDADES ANTIVIRALES DE COMPUESTOS NATURALES Y SEMI-SINTETICOS DE LA RESINA DE HELIOTROPIUM FILIFOLIUM