A New Strychnos Alkaloid from Strychnos Scheffleri

Author:

Tchinda Alembert T.12,Tane Pierre1,Sterner Olov3

Affiliation:

1. Department of Chemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon

2. Institute of Medical Research and Medicinal Plants Studies (IMPM), Center of Medicinal Plants Studies and Traditional Medicine (CRPMT), P.O. Box 6163, Yaoundé, Cameroon

3. Department of Organic and Bioorganic Chemistry, Lund Institute of Technology, SE 221 00 Lund, Sweden

Abstract

A phytochemical investigation of the stem bark of Strychnos scheffleri resulted in the isolation of a new strychnos alkaloid Na-deacetylmalagashine (1) together with the known derivative malagashine (2). Elucidation of the structures was based mainly on 1D and 2D NMR and MS studies and by comparison with related compounds.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference8 articles.

1. LeeuwenbergAJM. (1972) Flore du Cameroun. Museum National d'Histoire Naturelle. Paris 5e, 109–110.

2. Les Alcaloïdes majoritaires duStrychnos scheffleridu Zaire

3. SouthonI. W, BuckinghamJ. (1989) Dictionary of Alkaloids. Chapman & Hall, London, p. xxxvi.

4. Studies on argentine plants—XXXI

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