Antiproliferative Sesquiterpenes from the Red Sea Soft Coral Sarcophyton Glaucum-Reference-Cited by-同舟云学术

Antiproliferative Sesquiterpenes from the Red Sea Soft Coral Sarcophyton Glaucum

Published:2007-02 Issue:2 Volume:2 Page:1934578X0700200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Sawant Swapnali S.¹,Youssef Diaa T.A.²,Sylvester Paul W.¹,Wali Vikram¹,Sayed Khalid A. El¹

Affiliation:

1. Department of Basic Pharmaceutical Sciences, College of Pharmacy, 700 University Avenue, University of Louisiana at Monroe, Monroe, Louisiana 71209

2. Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

Abstract

The Red Sea soft coral Sarcophyton glaucum was investigated for its sesquiterpene content. A novel 1,2-dioxolane sesquiterpene alcohol, dioxosarcoguaiacol (1) along with the known (+)-alloaromadendrene are reported. The structure of the new sesquiterpene was determined on the basis of extensive spectral analyses. (+)-Alloaromadendrene showed potent inhibition of the proliferation of the highly malignant + SA mammary epithelial cells at a dose of 20μM.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0700200201

Reference12 articles.

1. Sarcophine, a new epoxy cembranolide from marine origin

2. Studies of australian soft corals—XXXV

3. Isoprenoids of the Soft Coral Sarcophyton glaucum: Nyalolide, a New Biscembranoid, and Other Terpenoids

4. Guaiane dimers from Xylopia vielana

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