Reactive Nitrogen Species Scavenging Capacity of Aqueous and Ethanolic Extracts from Galinsoga parviflora and G. quadriradiata Herbs

Author:

Rogowska Marta1,Srečec Siniša2,Bazylko Agnieszka1

Affiliation:

1. Department of Pharmacognosy and Molecular Basis of Phytotherapy, Warsaw Medical University, Banacha 1, 02-097 Warsaw, Poland

2. Križevci College of Agriculture, M. Demerca 1, HR-48260, Križevci, Croatia

Abstract

The aim of the study was to determine the scavenging capacity of aqueous and ethanolic extracts derived from the herb of two species of Galinsoga against NO and ONOO-. In both tests the aqueous extracts of both Galinsoga species were more active than the ethanolic extracts. The highest scavenging activity against NO, and also against ONOO- was shown by G. quadriradiata aqueous extract (SC50±SD=1.54±0.32, and 2.10±1.98, respectively). The study showed that the activity of the extracts from both Galinsoga species is related not only to the presence of flavonoids but also to caffeic acid derivatives and caffeic acid. The results of this study partly explain the beneficial effects of Galinsoga herb extracts in the treatment of skin diseases.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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