A New Cytotoxic Polyacetylenic Alcohol from a Sponge Callyspongia sp-Reference-Cited by-同舟云学术

A New Cytotoxic Polyacetylenic Alcohol from a Sponge Callyspongia sp

Published:2017-12 Issue:12 Volume:12 Page:1934578X1701201
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Balansa Walter¹²,Trianto Agus³,de Voogd Nicole J.⁴,Tanaka Junichi¹

Affiliation:

1. Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan

2. Department of Fisheries and Marine Science, Nusa Utara Polytechnic, Tahuna Sangihe Islands, North Sulawesi 95812, Indonesia

3. Department of Marine Sciences, Diponegoro University, Tembalang-Semarang, Central Java 50275, Indonesia

4. Naturalis Biodiversity Center, P. O. Box 9517, 2300 RA Leiden, The Netherlands

Abstract

A new cytotoxic polyacetylenic alcohol 1 was isolated from an Indonesian sponge Callyspongia sp. The structure of compound 1 was elucidated by spectral analyses and by applying modified Mosher's method. Compound 1 killed the cultured NBT-II rat bladder carcinoma cells at 5 and 10 μg/mL.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701201224

Reference16 articles.

1. Polyacetylenes of Marine Origin: Chemistry and Bioactivity

2. Swinholides and New Acetylenic Compounds from an Undescribed Species of Theonella Sponge

3. Bioactive marine metabolites III. A novel polyacetylene alcohol, inhibitor of cell division in fertilized sea urchin eggs, from the marine sponge tetrosia sp.

4. Two New Acetylenic Derivatives and a New Meroditerpenoid from a Taiwanese Marine Sponge Strongylophora durissima

5. Vasculyne, a New Cytotoxic Acetylenic Alcohol from the Marine Sponge Cribrochalina vasculum

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cytotoxic Alkylynols of the Sponge Cribrochalina vasculum: Structure, Synthetic Analogs and SAR Studies;Marine Drugs;2022-04-13

2. Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data;Marine Drugs;2021-11-26

3. Marine Natural Products from Indonesian Waters;Marine Drugs;2019-06-19