Rumphellolide J, an Ester of 4β,8β-Epoxycaryophyllan-5-ol and Rumphellaoic acid A, from the Gorgonian Rumphella antipathies

Author:

Lin Chi-Cheng1,Chung Hsu-Ming234,Su Yin-Di3,Peng Bo-Rong35,Wang Wei-Hsien34,Hwang Tsong-Long678,Wu Yang-Chang91011,Sung Ping-Jyun3491213

Affiliation:

1. Antai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung 928, Taiwan

2. Department of Applied Chemistry, National Pingtung University, Pingtung 900, Taiwan

3. National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan

4. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan

5. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University and Academia Sinica, Kaohsiung 804, Taiwan

6. Graduate Institute of Natural Products, College of Medicine and Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan

7. Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan

8. Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan

9. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan

10. Research Center for Natural Products and Drug Development, Kaohsiung Medical University, Kaohsiung 807, Taiwan

11. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan

12. Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan

13. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan

Abstract

Rumphellolide J (1), a novel sesquiterpenoid derivative, isolated from the gorgonian coral Rumphella antipathies, was determined to be an ester of 4β,8β-epoxycaryophyllan-5-ol and rumphellaoic acid by detailed spectroscopic analysis.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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