Chemical Constituents and Their Activities From the Seeds of Ormosia hosiei-Reference-Cited by-同舟云学术

Chemical Constituents and Their Activities From the Seeds of Ormosia hosiei

Published:2019-07 Issue:7 Volume:14 Page:1934578X1985997
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Xu Huiyou¹,Qiu Yatie¹,Chen Jingxin¹,Shi Yan¹,Zhang Xiaoqin²,Song Qiang³,Huang Mingqing²,Wu Zujian¹,Ni Lin¹

Affiliation:

1. College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, People’s Republic of China

2. College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, People’s Republic of China

3. Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, People’s Republic of China

Abstract

A new cytisine-like alkaloid, hosimonoal (1), with a fused monoterpene group, and 6 known compounds (2-6) were isolated from the seeds of Ormosia hosiei Hemsl. et Wils. The structure of the new compound was confirmed by high resolution electrospray ionization mass spectroscopy (HRESIMS), 1D and 2D nuclear magnetic resonance (NMR) spectroscopy, and electronic circular dichroism, and the others by 1H and 13C NMR spectroscopy and comparison with the literature data. In addition, compounds 1, 2, 3, and 6 showed moderate cytotoxic effects against A2780, A-549, HepG2, and MCF-7 cell lines with IC50 values ranging from 5.7 to 36.5 μM.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X19859977

Reference16 articles.

1. Constituents of the stem bark of Ormosia wayana

2. Distribution of Quinolizidine Alkaloid Types in Nine Ormosia Species (Leguminosae-Papilionoideae)

3. Alkaloid distribution in seeds of Ormosia, Pericopsis and Haplormosia

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