Anticancer Agents from Diverse Natural Sources

Author:

Khazir Jabeena1,Riley Darren L.1,Pilcher Lynne A.1,De-Maayer Pieter23,Mir Bilal Ahmad23

Affiliation:

1. Department of Chemistry, University of Pretoria, Pretoria 0028, South Africa

2. Centre for Microbial Ecology and Genomics, Department of Genetics, University of Pretoria, Pretoria 0028, South Africa

3. Genomics Research Institute, University of Pretoria, Pretoria 0028, South Africa

Abstract

This review attempts to portray the discovery and development of anticancer agents/drugs from diverse natural sources. Natural molecules from these natural sources including plants, microbes and marine organisms have been the basis of treatment of human diseases since the ancient times. Compounds derived from nature have been important sources of new drugs and also serve as templates for synthetic modification. Many successful anti-cancer drugs currently in use are naturally derived or their analogues and many more are under clinical trials. This review aims to highlight the invaluable role that natural products have played, and continue to play, in the discovery of anticancer agents.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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