Isoprenylated Flavonoids with PTP1B Inhibition from Ficus tikoua-Reference-Cited by-同舟云学术

Isoprenylated Flavonoids with PTP1B Inhibition from Ficus tikoua

Published:2015-12 Issue:12 Volume:10 Page:1934578X1501001
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Wu Lu-Qin¹,Lei Chun¹,Gao Li-Xin²,Liao Hai-Bing¹,Li Jing-Ya²,Li Jia²,Hou Ai-Jun¹

Affiliation:

1. Department of Pharmacognosy, School of Pharmacy, Fudan University, 826 Zhang Heng Road, Shanghai 201203, PR China

2. National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guo Shou Jing Road, Shanghai 201203, PR China

Abstract

Two new isoprenylated flavanones, ficustikousins A and B (1 and 2), together with seven known compounds (3–9) were isolated from the whole plant of Ficus tikoua (Moraceae). The structures of the new compounds were elucidated on the basis of spectroscopic methods. Compounds 1–7 exhibited moderate inhibitory activities against PTP1B in vitro.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1501001223

Reference24 articles.

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