Secondary Metabolites from Teclea amanuensis (Rutaceae) from Tanzania-Reference-Cited by-同舟云学术

Secondary Metabolites from Teclea amanuensis (Rutaceae) from Tanzania

Published:2008-10 Issue:10 Volume:3 Page:1934578X0800301
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Magadula Joseph J.¹²,Kapingu Modest C¹,Mbwambo Zakaria H.¹,Mulholland Dulcie A.²³

Affiliation:

1. Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, DSM, Tanzania

2. Natural Products Research Group, School of Chemistry, University of KwaZulu-Natal, 4041, Durban, SA

3. Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK

Abstract

The dichloromethane extract of the stem bark of Teclea amaniensis has yielded two novel furoquinoline alkaloids, 5-[3-methylbut-2-enyl]-4,6,7-trimethoxyfuro[2,3- b]quinoline and 6-(2′,3′-epoxy-3-methylbutyl)-5-hydroxyl-4,7-dimethoxyfuro[2,3- b]quinoline, in addition to an acridone alkaloid, 2-hydroxy-1,3-dimethoxy-10-methylacridone. Three known alkaloids, dictamnine, kokusaginine and evoxanthine, and two known triterpenoids, lupeol and lupeol acetate were also isolated. Structures of the new compounds were established by means of NMR spectroscopic and MS data.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0800301020

Reference11 articles.

1. Furoquinoline alkaloids from the southern African Rutaceae Teclea natalensis

2. The chemical systematics of the Rutaceae, subfamily Toddalioideae, in Africa

3. Quinoline alkaloids from the leaves of Teclea simplicifolia