Phytoconstituents of Genus Micromelum and Their Bioactivity—a Review

Author:

Thant Tin Myo12,Aminah Nanik Siti1ORCID,Kristanti Alfinda Novi1,Ramadhan Rico1,Aung Hnin Thanda3,Takaya Yoshiaki4

Affiliation:

1. Dept of Chemistry, Fac of Science and Technology, Universitas Airlangga, Komplek Kampus C UNAIR, Jl. Mulyorejo, Surabaya, Indonesia

2. Department of Chemistry, Mandalar Degree College, Mandalay, Myanmar

3. Department of Chemistry, Mandalay University, Myanmar

4. Faculty of Pharmacy, Meijo University, Yagotoyama, Tempaku, Nagoya, Japan

Abstract

The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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5. Susidarti RA. Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae).[PhD thesis]. Universiti Putra Malaysia; 2003.

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