Strychnuxinal, A New Alkaloid from Strychnos nux-blanda Fruits-Reference-Cited by-同舟云学术

Strychnuxinal, A New Alkaloid from Strychnos nux-blanda Fruits

Published:2018-05 Issue:5 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Sichaem Jirapast¹,Tip-Pyang Santi²,Lugsanangarm Kiattisak³,My Lien Do Thi⁴

Affiliation:

1. Department of Chemistry, Faculty of Science and Technology, Thammasat University Lampang Center, Lampang 52190, Thailand

2. Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand

3. Program of Chemistry, Faculty of Science and Technology, Bansomdejchaopraya Rajabhat University, Bangkok, 10600, Thailand

4. Department of Environmental Science, SaiGon University, Ho Chi Minh City 748355, Vietnam

Abstract

A new pyrrole alkaloid, strychnuxinal (1), along with ten known compounds (2–11) were isolated from the fruits of Strychnos nux-blanda. The structures of all the isolated compounds (1–11) were fully elucidated using spectroscopic data, as well as comparisons with the previous literature data. In addition, the absolute configuration of 1 at C-8 was determined by means of the ECD calculation. Moreover, all isolated compounds were evaluated for their acetylcholinesterase (AChE) inhibitory activity.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300505

Reference9 articles.

1. Alkaloids and a pimarane diterpenoid from Strychnos vanprukii

2. A New Non-glucosidic Iridoid from the Roots of Strychnos nux-blanda

3. Cytotoxic constituents fromSolanum lyratum