A Novel Alkaloid Isolated from Spiranthera Atlantica (Rutaceae)

Abstract

A novel alkaloid 3-hydroxy-4-(2-hydroxyethyl)-4′-methoxy-7′ H-quinolino[2,1- b]quinazolin-7′-one, named atlanticol (1), was isolated from Spiranthera atlantica (Rutaceae), along with five known compounds: lupeol (3), γ-fagarine (4), skimmianine (5), 7-methoxy-1-methyl-2-phenyl-4-quinolone (6) and 8-methoxy-1-methyl-2-phenyl-4-quinolone (7). Compound 6 was isolated from the Spiranthera genus for the first time. These compounds were characterized based on their spectral data, mainly through one and two-dimensional NMR and mass spectra, but also involving comparison with literature data.