A New Iridoid from the Aerial Parts of Hedyotis Pilulifera-Reference-Cited by-同舟云学术

A New Iridoid from the Aerial Parts of Hedyotis Pilulifera

Published:2016-03 Issue:3 Volume:11 Page:1934578X1601100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Hoai Nguyen Thi¹²,Duc Ho Viet¹,Phu Nguyen Dinh Quynh¹,Kodama Takeshi²,Ito Takuya²,Morita Hiroyuki²

Affiliation:

1. Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen, Hue City, Vietnam

2. Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930–0194, Japan

Abstract

A new iridoid, 10-acetylborreriagenin (1), and five known iridoid glycosides (2–6), were isolated from the aerial parts of Hedyotis pilulifera. Their structures were elucidated by spectral analyses, including 1D- and 2D-NMR, and HR-ESI-MS, and comparisons with the NMR data reported in the literature. The isolated compounds 1–6 were tested against six bacterial species. Among them, 10-acetylborreriagenin (1) showed antibacterial activity against Staphylococcus aureus, with an MIC value of 100 μg/mL.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601100311

Reference21 articles.

1. Phylogeny of Hedyotis L. (Rubiaceae: Spermacoceae): Redefining a complex Asian-Pacific assemblage

2. Two New β-Carboline Alkaloids fromHedyotis capitellatavar.mollis

3. Capitelline - A New Indole Alkaloid fromHedyotis capitellata

4. Anthraquinones from Hedyotis capitellata

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