Synthesis and Antimicrobial Activities of Some Sulphur Containing Chromene Derivatives

Author:

Şerbetçi Tuba1,Birteksöz Seher2,Prado Soizic3,Michel Sylvie3,Tillequin François3

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, 34116 Istanbul, Turkey

2. Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Istanbul University, 34116 Istanbul, Turkey

3. Laboratoire de Pharmacognosie de l'Université Paris Descartes, U.M.R./C.N.R.S. 8638, Faculté de Pharmacie, 4 Avenue de l'Observatoire, 75006 Paris, France

Abstract

A series of 3,3-dimethyl-3 Hbenzothieno[3,2- f][1]-benzopyran analogues modified at the pyran 1,2-double bond were synthesized. The corresponding dihydro and (±)-cis-diol derivatives were converted into diacetate and cyclic carbonate upon acylation. The title compounds were characterized by spectroscopic analysis and screened for their antimicrobial activity in vitro.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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