Second Generation Synthesis of the Neo-Clerodane Diterpenoid Methyl Barbascoate-Reference-Cited by-同舟云学术

Second Generation Synthesis of the Neo-Clerodane Diterpenoid Methyl Barbascoate

Published:2013-07 Issue:7 Volume:8 Page:1934578X1300800
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Hagiwara Hisahiro¹,Honma Naomi¹,Kinugawa Kimihiko¹,Sato Shota¹,Hoshi Takashi²,Suzuki Toshio²

Affiliation:

1. Graduate School of Science and Technology, Niigata University, 8050, 2-Nocho, Ikarashi, Nishi-ku, Niigata 950-2181, Japan

2. Faculty of Engineering, Niigata University, 8050, 2-Nocho, Ikarashi, Nishi-ku, Niigata 950-2181, Japan

Abstract

The second generation total synthesis of the neo-clerodane diterpenoid, methyl barbascoate, was accomplished in seven or nine linear steps via double enol triflation and subsequent palladium catalyzed double carbonylation, followed by regioselective samarium diiodide mediated conjugate reduction.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1300800706

Reference23 articles.

1. Neoclerodane Diterpenes as a Novel Scaffold for μ Opioid Receptor Ligands

2. Salvinorin A Analogs as Probes in Opioid Pharmacology

3. Natural Products as Tools for Neuroscience: Discovery and Development of Novel Agents to Treat Drug Abuse

4. Synthesis of Clerodane Diterpenoids and Related Compounds - Stereoselective Construction of the Decalin Skeleton with Multiple Contiguous Stereogenic Centers

5. The First Total Synthesis of (−)-Methyl Barbascoate

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unexpected Racemization in the Course of the Acetalization of (+)-(S)-5-Methyl-Wieland–Miescher Ketone with 1,2-Ethanediol and TsOH under Classical Experimental Conditions;International Journal of Molecular Sciences;2019-12-05