Affiliation:
1. Department of Chemistry Graduate School of Science Osaka Prefecture University Sakai Osaka 599-8531 Japan
Abstract
A novel palladium-catalyzed intramolecular oxidative alkylation of unactivated olefins is described. This protocol was devised to solve one of the drawbacks of the original palladium-catalyzed cycloalkenylation that we developed. We call this new procedure the ‘second generation palladium-catalyzed cycloalkenylation’. This protocol has been applied to the total syntheses of cis-195A trans-195A boonein scholareins A C D and α-skytanthine.
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine