A GC-FID Validated Method for the Quality Control of Eucalyptus globulus Raw Material and its Pharmaceutical Products, and GC-MS Fingerprinting of 12 Eucalyptus Species

Abstract

In this work we have validated a method to standardize and control the quality of Eucalyptus globulus raw material and phytomedicines containing either the essential oil or the fluid extract of this plant in the final formulation. Internal standardization provided a simple, fast, and reproducible GC-FID analytical method that accurately quantified 1,8-cineol in different E. globulus sub-products, such as its essential oil, dried leaves, fluid extract, and syrup. In addition, GC-MS identification of the main compounds of E. globulus species afforded fingerprints for the qualitative analysis of different Eucalyptus species.