Metabolites of the Endophytic Fungus Penicillium sp. FJ-1 of Acanthus ilicifolius-Reference-Cited by-同舟云学术

Metabolites of the Endophytic Fungus Penicillium sp. FJ-1 of Acanthus ilicifolius

Published:2014-06 Issue:6 Volume:9 Page:1934578X1400900
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Liu Jian-Fang¹,Chen Wei-Jie²,Xin Ben-Ru¹,Lu Jie³

Affiliation:

1. Department of Pharmaceutics, People's Hospital of Rizhao, Rizhao 276826, P.R. China

2. Department of Neurosurgery, People's Hospital of Rizhao, Rizhao 276826, P.R. China

3. Department of Natural Medicinal Chemistry, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, P.R. China

Abstract

Two new compounds, named as (2 R,3 S)-pinobanksin-3-cinnamate (1), and 15α-hydroxy-(22 E,24 R)-ergosta-3,5,8(14),22-tetraen-7-one (2), were isolated from the endophytic fungus Penicillium sp. FJ-1 of Acanthus ilicifolius Linn. Their structures were elucidated on the basis of spectroscopic analysis. Additionally, compound 1 exhibited potent neuroprotective effects on corticosterone-damaged PC12 cells, and compound 2 showed potent cytotoxicity on glioma cell lines.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900617

Reference15 articles.

1. Structure elucidation of five new iridoid glucosides from the leaves ofAvicennia marina

2. TNF-α inhibitory diterpenoids from the Chinese mangrove plant Excoecaria agallocha L.

3. A New Dolabrane-type Diterpene from Ceriops tagal

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