Three New Glycosides From the Stems of <i>Derris elliptica</i>-Reference-Cited by-同舟云学术

Three New Glycosides From the Stems of Derris elliptica

Published:2022-09 Issue:9 Volume:17 Page:1934578X2211262
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Trang Bui Thi Thu¹²,Nhiem Nguyen Xuan¹³,Thi Huong Nguyen²,Thi Thanh Mai Nguyen²,Tuan Anh Nguyen²,Van Kiem Phan¹³^ORCID

Affiliation:

1. Faculty of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam

2. Faculty of Chemistry Technology, Hanoi University of Industry, Hanoi, Vietnam

3. Department of Molecule Structure Research, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam

Abstract

Three new glycosides, derriacuminosides A-C (1-3), were isolated from the stems of Derris elliptica (Wall.) Benth. Their chemical structures were determined by interpretations of HRESIMS and NMR spectra. The anti-inflammatory activity of compounds 1-3 were evaluated by inhibiting NO production in LPS activated RAW264.7 cells. Compounds 1-3 potentially inhibited NO production with IC50 values of 26.54 ± 3.08, 26.35 ± 1.37, and 49.71 ± 2.93 µM, respectively, compared to the positive control, L-NMMA (IC50 35.56 ± 2.98 µM).

Funder

Graduate University of Science and Technology

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X221126299

Reference15 articles.

1. 239. The active principles of leguminous fish-poison plants. Part II. The isolation of 1-elliptone from Derris elliptica

2. BIOCHEMICAL STUDIES OF DEREIS AND MUNDULEA: THE HISTOLOGY OF ROTENONE IN DEREIS ELLIPTIC A

3. Development and Evaluation of Granule and Emulsifiable Concentrate Formulations Containing Derris elliptica Extract for Crop Pest Control

4. Antimicrobial activity of the Derris elliptica, Derris indica and Derris trifoliata extractives

5. A Further Rotenoid fromDerris elliptica