Chemical and Biological Activity of Triterpene Saponins from Medicago Species

Author:

Tava Aldo1,Avato Pinarosa2

Affiliation:

1. C.R.A. Istituto Sperimentale per le Colture Foraggere, viale Piacenza 29, 26900 Lodi, Italy

2. Dipartimento Farmaco-Chimico, Universitá di Bari, via Orabona 4, 70125 Bari, Italy

Abstract

Naturally occurring saponins are a large group of triterpene and steroid glycosides characterized by several biological and pharmacological properties. The Medicago genus represents a valuable source of saponins which have been extensively investigated. This review summarizes the chemical features of saponins from Medicago species and their biological activity, with particular attention to their antimicrobial, insecticidal, allelopathic and cytotoxic effects. Influence of saponins on animal metabolism is also reported.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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