Cladieunicellin J, a New Hydroperoxyeunicellin from Cladiella sp-Reference-Cited by-同舟云学术

Cladieunicellin J, a New Hydroperoxyeunicellin from Cladiella sp

Published:2014-05 Issue:5 Volume:9 Page:1934578X1400900
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Chen Tsung-Hung¹²,Cheng Ching-Hsiao³,Chen Yung-Husan²,Lu Mei-Chin¹²,Fang Lee-Shing⁴,Chen Wu-Fu³,Wen Zhi-Hong⁵,Wang Wei-Hsien²⁵,Wu Yang-Chang⁶⁷⁸,Sung Ping-Jyun¹²⁷⁹

Affiliation:

1. Graduate Institute of Marine Biotechnology, Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan

2. National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan

3. Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan

4. Department of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan

5. Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan

6. School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan

7. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan

8. Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan

9. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan

Abstract

A new 6-hydroperoxyeunicellin diterpenoid, designated as cladieunicellin J (1), was isolated from an octocoral Cladiella sp., and its structure elucidated by spectroscopic methods. Compound 1 was found to exhibit cytotoxicity toward CCRF-CEM human T-cell acute lymphoblastic leukemia.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900504

Reference13 articles.

1. Cladieunicellins A-E, New Eunicellins from an Indonesian Soft Coral Cladiella sp.

2. Discovery of New Eunicellins from an Indonesian Octocoral Cladiella sp.

3. New 6-Hydroxyeunicellins from a Soft Coral Cladiella sp.

4. Cladieunicellin H, a New Hemiketal Eunicellin-Based Diterpenoid from the Octocoral Cladiella sp

5. Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.

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