New Oxygenated Steroid from the Marine-Derived Fungus Aspergillus flavus-Reference-Cited by-同舟云学术

New Oxygenated Steroid from the Marine-Derived Fungus Aspergillus flavus

Published:2018-08 Issue:8 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Yang Meng-Yue¹,Yang Jian-Kun¹,Yang Jin-Kai²,Hu Lian-Dong¹,Zhu Hua-Jie¹,Cao Fei¹

Affiliation:

1. Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnostics of Education Ministry of China, College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China

2. Department of Emergency, the 252nd Hospital of PLA, Baoding, 071000, China

Abstract

One new oxygenated steroid, named aspersteroid A (1), and three known analogues (2–4) were isolated from the marine-derived fungus Aspergillus flavus collected from the Bohai Sea. Their structures were elucidated by spectroscopic analyses and by comparison with previously reported data. The absolute configuration of tetracyclic nucleus in 1 was assigned by quantum chemical calculation of the electronic circular dichroism (ECD) spectrum. All the compounds were evaluated for their cytotoxic and antibacterial activities.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300807

Reference16 articles.

1. Marine natural products

2. Unusual C25 Steroid Isomers with Bicyclo[4.4.1]A/B Rings from a Volcano Ash-Derived Fungus Penicillium citrinum

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4. Two New Diketomorpholine Derivatives and a New Highly Conjugated Ergostane-Type Steroid from the Marine Algal-Derived Endophytic Fungus Aspergillus alabamensis EN-547

5. Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus Oryzae

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1. Marine natural products;Natural Product Reports;2020

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