A New Noroleanane from the Seeds of Trichosanthes kirilowii-Reference-Cited by-同舟云学术

A New Noroleanane from the Seeds of Trichosanthes kirilowii

Published:2018-07 Issue:7 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Xu Liang¹,Tang Chun-Feng²,Wu Cui¹,Ma Yu-Cui¹,Chao Zhi-Mao¹

Affiliation:

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China

2. Guangxi Botanical Garden of Medicinal Plant, Nanning, 530023, China

Abstract

A new noroleanane named as karounitriol (1), together with four known compounds, 7-oxodihydrokarounidiol (2), isokarounidiol (3), karounidiol (4), and stigmasta-7,22-dien-3β-ol were isolated from the seeds of Trichosanthes kirilowii Maxim. Structure of the new compound was elucidated as 3α,7β,29-trihydroxy-D:C-friedo-olean-8-ene on the basis of spectroscopic methods including extensive 1D NMR (1H, 13C), 2D NMR (1H-1H COSY, DEPT, HMQC, HMBC, and NOESY), IR, and MS studies.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300707

Reference17 articles.

1. Nanjing University of Chinese Medicine (2006) The Dictionary of Chinese Materia Medica. Shanghai Science and Technology Press, Shanghai, 2534–2535.

2. Seeds of Trichosanthes kirilowii, an Energy-Rich Diet

3. Hanultarin, a cytotoxic lignan as an inhibitor of actin cytoskeleton polymerization from the seeds of Trichosanthes kirilowii

4. An Isoaurone and Other Constituents fromTrichosanthes kirilowiiSeeds Inhibit Hypoxia-Inducible Factor-1 and Nuclear Factor-κB