Minor Ent-abietane Diterpenoids from Euphorbia guyoniana

Author:

Haba Hamada1,Marcourt Laurence2,Benkhaled Mohammed1,Long Christophe2

Affiliation:

1. Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Département de Chimie, Faculté des Sciences, Université de Batna, Batna 05000, Algeria

2. Centre de Recherche sur les Substances Naturelles, UMS CNRS 2597, 3 rue des Satellites, BP 94244, 31432 Toulouse, France

Abstract

Three new abietane-type diterpenoids: ent-abieta-8,11,13-trien-16-ol (1), ent-abieta-8,11,13-trien-11,16-diol (2) and 11,12-dihydroxy-7-oxo- ent-abieta-8,11,13-trien-16-oic acid methyl ester (3), in addition to three known triterpenoids: euphol (4), 24,25-epoxycycloartanol (5) and β-sitosterol O-β-D-glucoside (6) were isolated from the chloroform extract of the roots of Euphorbia guyoniana. Structures of the isolated compounds were established on the basis of spectroscopic analyses, including 1D and 2D homo and heteronuclear NMR experiments and ESIMS, and comparison with literature data.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

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