Antioxidant Metabolites from the Stems of Bakeridesia gaumeri-Reference-Cited by-同舟云学术

Antioxidant Metabolites from the Stems of Bakeridesia gaumeri

Published:2017-09 Issue:9 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Escalante-Erosa Fabiola¹,Ruiz-Vargas Javier A.¹,Gómez-Guzmán Alonso¹,Waltenberger Birgit²,Stuppner Hermann²,Peña-Rodríguez Luis M.¹

Affiliation:

1. Laboratorio de Química Orgánica, Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, calle 43 No. 130, Col. Chuburná de Hidalgo, Mérida, Yucatán, México CP 97205

2. Institute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80–82, A-6020 Innsbruck, Austria

Abstract

Bakeridesia gaumeri is an endemic plant of the Yucatan peninsula, where it is used in traditional medicine for the treatment of dysentery, enterocolitis and diarrhea. The stem extract of the plant showed significant antioxidant activity in the DPPH free radical scavenging assay. Bioassay-guided fractionation of the crude extract resulted in the isolation and identification of 7-hydroxycadalenal (1, EC50 0.85 ± 0.06 mM) and trans-clovamide (2, EC50 0.15 ± 0.01 mM) as the metabolites responsible for the antioxidant activity of the crude extract.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200923

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