Synthesis and Cytotoxic Evaluation of Glucoconjugated Ethylmompain Derivatives-Reference-Cited by-同舟云学术

Synthesis and Cytotoxic Evaluation of Glucoconjugated Ethylmompain Derivatives

Published:2017-09 Issue:9 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Pokhilo Natalia D.¹,Atopkina Lyubov N.¹,Kiseleva Marina I.¹,Denisenko Vladimir A.¹,Anufriev Victor Ph.¹

Affiliation:

1. G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, 690022, Vladivostok, Prospect 100 let Vladivostoku, 159, Russia

Abstract

Quinone-carbohydrate conjugates of ethylmompain, a pigment of the sea urchin Echinothrix diadema, and its chlorinated analog were synthesized. The cytotoxic activity and contraceptive properties of the synthesized compounds have been investigated using the sperm and eggs of the sea urchin Strongylocentrotus intermedius.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200924

Reference30 articles.

1. Anti-Cancer Activities of 1,4-Naphthoquinones: A QSAR Study

2. Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

3. Synthesis of carbohydrate-based naphthoquinones and their substituted phenylhydrazono derivatives as anticancer agents

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