Alkaloids from the Bulbs of Boophone disticha

Author:

van Rensburg Elmarie1,Zietsman Pieter C.12,Bonnet Susan L.3,Wilhelm Anke3

Affiliation:

1. National Museum, Bloemfontein, 9300, Free State, South Africa

2. Centre for Environmental Management, University of the Free State, Bloemfontein, 9301, Free State, South Africa

3. Department of Chemistry, University of the Free State, Bloemfontein, 9301, Free State, South Africa

Abstract

Boophone disticha is widely used in South African traditional medicine. Several of its biological properties can be corroborated via its alkaloid constituents. Previous research on this plant led to the isolation of several alkaloids, mainly of the crinane alkaloid group of the Amaryllidaceae. In the present study, one new compound 1- O-acetylbuphanamine (1) and four known crinane alkaloids were isolated chromatographically from the ethanol extract of the bulbs of B. disticha. Their structures were determined via spectroscopic methods, including 1D and 2D NMR, ESI-MS, HRMS and IR data.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference22 articles.

1. Alkaloids of the South African Amaryllidaceae: A Review

2. ViladomatF, BastidaJ, CodinaC, NairJJ, CampbelWE. (1997) Alkaloids of the South African Amaryllidaceae. In Recent Research Developments in Phytochemistry. Vol. 1. PandalaiSG. Ed. Research Signpost Publishers. Trivandrum, India.

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