Dinimbidiol Ether, a Novel Bioactive Dimeric Diterpene from the Root Extract of Cnidoscolus souzae-Reference-Cited by-同舟云学术

Dinimbidiol Ether, a Novel Bioactive Dimeric Diterpene from the Root Extract of Cnidoscolus souzae

Published:2017-09 Issue:9 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

García-Sosa Karlina¹,Aldana-Pérez Rodolfo¹,Moo Reyna V. Ek¹,Simá-Polanco Paulino²,Peña-Rodríguez Luis M.¹

Affiliation:

1. Laboratorio de Química Orgánica, Unidad de Biotecnología, Centro de investigación Científica de Yucatán, Calle 43 No.130, Col. Chuburná de Hidalgo, CP 97205, Mérida, Yucatán, México

2. Unidad de Recursos Naturales, Centro de investigación Científica de Yucatán, Calle 43 No.130, Col. Chuburná de Hidalgo, CP 97205, Mérida, Yucatán, México

Abstract

The radical scavenging assay-guided fractionation of the root extract of Cnidoscolus souzae resulted in the isolation and identification of a novel bioactive dimeric diterpene with an ether linkage which has been designated as dinimbidiol ether (2). Evaluation of the antioxidant activity using the DPPH reduction assay showed that 2 is the most active metabolite in the crude extract of the plant.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200903

Reference9 articles.

1. Bioactive Metabolites from Cnidoscolus souzae and Acmella pilosa

2. A New Abietane and Two Dimeric Abietane Diterpenes from the Black Heartwood of Cryptomeria japonica

3. Premnalatifolin A, a novel dimeric diterpene from Premna latifolia Roxb

4. Diterpenoids

5. Grandione, a new heptacyclic dimeric diterpene from Torreya grandis Fort.

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